Microglial cell lines are a useful alternative to in vivo studies as they are amenable to high-throughput assays and genetic manipulation.

DSMZ Tools for Diving into Cell Line Data
Enable decision-making on the best cell model for research questions by provision of curated data.

In 2006 Sellers (Novartis), Garraway (Broad Institute) and Schlegel (Novartis) crafted the initial project plan for large-scale genetic characterization of ~1000 cancer cell lines. This project was subsequently renewed on two occasions and hence we think of these as the three phases of the CCLE project.

Cellosaurus, a cell line database, cell line catalogue, cell line ontology.